Create a responsive wireframe
A nice little tutorial about using Wirefy to build responsive wireframes. Personally I would approach Foundation and Bootstrap in the same way.
If you’ve worked with responsive design some time in the last two years, you will have probably heard this comment from clients at least once: “I don’t get it. You’re going to build two sites”. The problem with discussing flow, structure and hierarchy across various screens and technologies is that our clients are still trying to catch up to these ideas.
An excerpt from Create a responsive wireframe