Killer Responsive Layouts With CSS Regions
Regions is something new for the CSS specification. Not all browsers have jumped on board just yet but this article provides us with some practical approaches as to how it might benefit a responsive layout in the future.
CSS regions enable us to disperse content across multiple containing elements. They provide a flow, which consists of content that may appear within multiple elements, and a region chain, which is the collection of elements the flow is spread across.
An excerpt from Killer Responsive Layouts With CSS Regions